Lecef 500 100 Tablets For urinary tract gynaecological Gonorrhoea bone

dental infections

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Cefalexin or LECEF is a first-generation cephalosporin antibiotic, introduced in 1967 by Eli Lilly and Company. It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents' cefalotin and cefazolin. It is commonly marketed under the trade name Keflex (Lilly), Sporidex (Ranbaxy) or Nufex.

LECEF is an antibiotic. It is used to treat certain bacterial infections of the nose, throat, chest, ears, skin, bones, genitals or bladder. LECEF can also be used to prevent infection when you undergo specific dental procedures. LECEF belongs to a group of antibiotics called the cephalosporins.

Typical usage: Respiratory tract infections, ENT, urinary tract, gynaecological and obstetric infections. Gonorrhoea (when penicillin is unsuitable). Skin, soft tissue, bone and dental infections.

Side Effects: Hypersensitivity reactions, interstitial nephritis, vulvovaginitis, dizziness, headache, nausea, vomiting, diarrhoea, skin reactions, vaginitis, genital moniliasis, vaginal discharge, neutropenia.

Drug Interaction: Cephalexin is known to interact with other drugs like pivmecillinam (HCl), probenecid, protamine (sulphate), reviparin sodium, streptomycin.

Mechanism Of Action: Cefalexin, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; cefalexin may interfere with an autolysin inhibitor.